What does Title 21 primarily deal with?

Title 21 of the United States Code primarily addresses issues related to controlled substances and the regulation of drug enforcement. It establishes the legal framework surrounding the manufacture, distribution, and use of various drugs, particularly those that are classified as illegal or controlled substances. This title outlines the regulations that enforce safe and legal practices regarding drug use and trafficking, emphasizing the government's role in combating drug abuse and trafficking.

The focus on controlled substances violations distinguishes Title 21 from other legal titles that may cover a range of topics such as weapons, taxation, or immigration. Each of those areas is governed by separate legal frameworks—such as Title 18 for crimes related to weapons or Title 26 for federal tax law—highlighting how Title 21 uniquely centers on drug-related issues.